Rehydrate the desiccated vial with accompanying diluent and shake well. Inject 2mL subcutaneously or intramuscularly using aseptic technique. Immunization against BRSV requres a second dose of bovine respiratory syncytial virus (Titanium BRSV) vaccine to be given 14 to 28 days after the first dose. Annual revaccination is recommended. Calves vaccinated before weanting should be revaccinated 30 days after weaning when the possible influence of maternal antibodies is decreased.